(5-氯噻吩-3-基)甲醇合成路线 （共 4 条）
反应条件
manganese(IV) oxide in dichloromethane T=20°C; 15 h;
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1405852 A1, 2004 ;
Location in patent: Page 219 ;
EP 1405852 A1
反应条件
1: With chloroformic acid ethyl ester; triethylamine in tetrahydrofuran
T=20°C; 2.5 h;
2: With sodium tetrahydroborate in tetrahydrofuran; water
T=20°C; 18.5 h;
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1577301 A1, 2005 ;
Location in patent: Page/Page column 240 ;
反应条件
sodium borohydride; sodium hydrogencarbonate; acetic acid; triethylamine in tetrahydrofuran; dichloromethane; water
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: US2005/20645 A1, 2005 ;
反应条件
triethylamine
T=20°C; 2.5 h;
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1405852 A1, 2004 ;
Location in patent: Page 218 ;
EP 1405852 A1
