2-(1H-咪唑-1-基)-1-[4-(2-苯基乙基)苯基]乙烷-1-酮合成路线 （共 5 条）
反应条件
in N-methyl-acetamide
参考文献
Recordati S.A.
Patent: US4275071 A1, 1981 ;
反应条件
in N,N-dimethyl-formamide
T=5 - 10°C; 24 h;
参考文献
Nardi; Tajana; Leonardi; Pennini; Portioli; Magistretti; Subissi
Journal of Medicinal Chemistry, 1981 , vol. 24, # 6 p. 727 - 731
反应条件
sodium hydroxide in water
Yield given;
参考文献
Kamijo; Yamamoto; Harada; Iizuka
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 4 p. 1213 - 1221
反应条件
1: acetonitrile / Ambient temperature
2: NaOH / H2O
View Scheme
参考文献
Kamijo; Yamamoto; Harada; Iizuka
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 4 p. 1213 - 1221
反应条件
sodium tetrahydroborate in methanol
2 h; Heating;
参考文献
Nardi; Tajana; Leonardi; Pennini; Portioli; Magistretti; Subissi
Journal of Medicinal Chemistry, 1981 , vol. 24, # 6 p. 727 - 731
