吡唑并[1,5-a]吡啶-3-甲醛合成路线 (共 4 条)
反应条件
manganese(IV) oxide in tetrahydrofuran 1.5 h; Reflux;
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 13 p. 4752 - 4772
反应条件
1-methyl-piperazine; sodium bis(2-methoxyethoxy)aluminium dihydride in toluene 14 h; Ambient temperature;
参考文献
Gmeiner; Schuenemann
Archiv der Pharmazie, 1988 , vol. 321, # 9 p. 517 - 520
反应条件
trichlorophosphate 1 h; Ambient temperature;
参考文献
Tanji, Ken-ichi; Sasahara, Takehiko; Suzuki, Junko; Higashino, Takeo
Heterocycles, 1993 , vol. 35, # 2 p. 915 - 924
反应条件
palladium on activated charcoal; hydrogen in ethanol T=20 - 60°C; Inert atmosphere;
参考文献
ENVIVO PHARMACEUTICALS, INC.; RIPKA, Amy; SHAPIRO, Gideon; MCRINER, Andrew, J.; BURSAVICH, Matthew, Gregory
Patent: WO2013/142269 A1, 2013 ;
Location in patent: Paragraph 0704; 0705 ;