反应条件
1: NaBH4 / methanol / 1 h / -4 °C
2: methanesulfonyl chloride, triethylamine / CH2Cl2 / -20 deg C to r.t.
3: 95 percent / LiAlH4 / tetrahydrofuran / 1 h
4: 1) diisopropylamine/n-BuLi / 1) THF, hexane, HMPA, -20 deg C, 2 h 2) -78 deg C, 1 h
5: 70 percent / HgCl2, CaCO3 / acetonitrile; H2O / 1 h / 50 °C
View Scheme
参考文献
Chamberlin, A.Richard; Nguyen, Hoa D.; Chung, John Y.L.
Journal of Organic Chemistry, 1984 , vol. 49, # 10 p. 1682 - 1688
