反应条件
1: ethyl bromide With magnesium in tetrahydrofuran T=50°C; 2: 2,4-dichloro-5-fluoro-pyrimidine in tetrahydrofuran; ethylene glycol dimethyl ether T=0 - 15°C; 1 h; 3: With iodine; triethylamine in tetrahydrofuran; ethylene glycol dimethyl ether T=5 - 15°C;
参考文献
Butters, Mike; Ebbs, Julie; Green, Stuart P.; MacRae, Julie; Morland, Matthew C.; Murtiashaw, Charles W.; Pettman, Alan J.
Organic Process Research and Development, 2001 , vol. 5, # 1 p. 28 - 36