5,6,8,9-四氢-2-硝基-7H-苯并-7-环庚酮合成路线 (共 3 条)
反应条件
sulfuric acid; nitric acid in water
T=0°C; 2 h;
参考文献
WARNER-LAMBERT COMPANY LLC
Patent: WO2004/69244 A1, 2004 ;
Location in patent: Page/Page column 79; 80 ;
反应条件
sulfuric acid; nitric acid in nitromethane; water
T=0°C; 3.16667 h;
参考文献
RIGEL PHARMACEUTICALS, INC.; SINGH, Rajinder; HECKRODT, Thilo, J.; HOLLAND, Sacha
Patent: WO2010/5876 A2, 2010 ;
Location in patent: Page/Page column 56 ;
WO 2010/005876 A2
反应条件
hydrogen; palladium 10 on activated carbon in methanol
P=2068.65 Torr; 4 h;
参考文献
WARNER-LAMBERT COMPANY LLC
Patent: WO2004/69244 A1, 2004 ;
Location in patent: Page/Page column 80 ;