7-氨基-10-去氨基甲酰氧基-9-去氢-7-去甲氧基丝裂霉素B合成路线 （共 5 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran
96 h; Ambient temperature;
参考文献
Kono, Motomichi; Kasai, Masaji; Shirahata, Kunikatsu
Synthetic Communications, 1989 , vol. 19, # 11-12 p. 2041 - 2048
反应条件
ammonium hydroxide in methanol
4 h; Ambient temperature;
参考文献
Kono, Motomichi; Kasai, Masaji; Shirahata, Kunikatsu
Synthetic Communications, 1989 , vol. 19, # 11-12 p. 2041 - 2048
反应条件
1: 60 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene / tetrahydrofuran / 120 h / 5 °C
2: 90 percent / aq. ammonia / methanol / 4 h / Ambient temperature
View Scheme
参考文献
Kono, Motomichi; Kasai, Masaji; Shirahata, Kunikatsu
Synthetic Communications, 1989 , vol. 19, # 11-12 p. 2041 - 2048
反应条件
1,5-diazabicyclo[5.4.0]undeca-5-ene in tetrahydrofuran
43 h; Heating; Yields of byproduct given;
参考文献
Kasai, Masaji; Kono, Motomichi; Shirahata, Kunikatsu
Journal of Organic Chemistry, 1989 , vol. 54, # 25 p. 5908 - 5911
反应条件
1: methanolic NH3 / 1 h / Ambient temperature
2: 1,5-diazabicyclo<5.4.0>undec-5-ene / tetrahydrofuran / 43 h / Heating
View Scheme
参考文献
Kasai, Masaji; Kono, Motomichi; Shirahata, Kunikatsu
Journal of Organic Chemistry, 1989 , vol. 54, # 25 p. 5908 - 5911
