7-氟-3-甲基-4-(4-甲基哌嗪-1-基)-5H-噻吩并[3,2-c][1,5]苯并二氮杂卓合成路线 （共 2 条）
反应条件
titanium tetrachloride in various solvent(s)
T=120°C; 2 h;
参考文献
Chakrabarti, Jiban K.; Horsman, Linda; Hotten, Terrence M.; Pullar, Ian A.; Tupper, David E.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 8 p. 878 - 884
反应条件
1: hydrogen / 10percent Pd/C / ethanol; ethyl acetate / 3102.9 Torr
2: TiCl4 / various solvent(s) / 1.) 120 deg C, 4 h, 2.) reflux, overnight
View Scheme
参考文献
Chakrabarti, Jiban K.; Horsman, Linda; Hotten, Terrence M.; Pullar, Ian A.; Tupper, David E.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 8 p. 878 - 884
