(S)-(-)-1,2,3,4-四氢异喹啉-3-羧酸合成路线 （共 45 条）
反应条件
1: NaOMe / 4 h / Heating 2: 6 N aq. HCl / 4 h / Heating 3: 83 percent / p-TsOH*H2O / toluene / 30 h / Heating 4: 94 percent / NaOH / methanol / 6 h / Ambient temperature View Scheme
参考文献
Synthesis, , # 11 p. 1157 - 1160
反应条件
1: 6 N aq. HCl / 4 h / Heating 2: 83 percent / p-TsOH*H2O / toluene / 30 h / Heating 3: 94 percent / NaOH / methanol / 6 h / Ambient temperature View Scheme
参考文献
Synthesis, , # 11 p. 1157 - 1160
反应条件
1: BF3*OEt2 / 20 °C 2: 72 percent / H2O / propan-2-ol / 20 °C View Scheme
参考文献
Synthesis, , # 10 p. 1513 - 1518
反应条件
1: 86 percent / 6 N aq. HCl / 4 h / Heating 2: 83 percent / p-TsOH*H2O / toluene / 30 h / Heating 3: 94 percent / NaOH / methanol / 6 h / Ambient temperature View Scheme
参考文献
Synthesis, , # 11 p. 1157 - 1160
反应条件
water Hydrolysis; epimerization; 12 h; Heating; Title compound not separated from byproducts.;
参考文献
Journal of Organic Chemistry, , vol. 65, # 22 p. 7310 - 7322
反应条件
chicken liver acetone; water pH=7.5;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 10 p. 1399 - 1401
反应条件
chicken liver acetone; water pH=7.5; 2 h;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 10 p. 1399 - 1401
反应条件
1: 69 percent / conc. HCl View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 64, # 12 p. 3729 - 3731
反应条件
hydrogenchloride; water Reflux;
参考文献
Chinese Chemical Letters, , vol. 23, # 3 p. 297 - 300
反应条件
sodium hydrogencarbonate in water T=20°C; 1.5 h;
参考文献
Tarver Jr.; Pfizenmayer; Joullie
Journal of Organic Chemistry, 2001 , vol. 66, # 23 p. 7575 - 7587
