1-(2-甲氧基苯基)乙醇合成路线 （共 37 条）
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 0.5 h; 2: With sodium hydroxide; water in tetrahydrofuran
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2005/75435 A1, 2005 ;
Location in patent: Page/Page column 139 ;
WO 2005/075435 A1
反应条件
lithium aluminium tetrahydride in diethyl ether 1 h; Heating;
参考文献
Timmermans, Johan L.; Wamelink, Marc P.; Lodder, Gerrit; Cornelisse, Jan
European Journal of Organic Chemistry, 1999 , # 2 p. 463 - 470
反应条件
pinacol borane; 4 A molecular sieve; Rh(2,5-norbornadiene)2BF4 in ethylene glycol dimethyl ether T=20°C; 12 h; Title compound not separated from byproducts.;
参考文献
Angewandte Chemie - International Edition, , vol. 47, # 5 p. 894 - 897
反应条件
caesium carbonate in acetone T=20°C; 0.833333 h;
参考文献
WO2003/103653 A1, ;
Page 184-185 ;
WO 03/103653 A1
反应条件
4,4'-di-tert-butylbiphenyl; lithium in tetrahydrofuran T=-40°C; Wittig rearrangement; 1 h;
参考文献
Gomez, Cecilia; Macia, Beatriz; Lillo, Victor J.; Yus, Miguel
Tetrahedron, 2006 , vol. 62, # 42 p. 9832 - 9839
参考文献
US5559111 A1, ;
US 5559111 A
反应条件
1: 2-methoxybromobenzene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 2.5 h; 2: ethylene glycol cyclic sulfate in tetrahydrofuran; hexane T=20°C; 16 h; 3: With sulfuric acid in tetrahydrofuran; hexane 72 h; Heating; Further stages.;
参考文献
Synthesis, , # 11 p. 1793 - 1797
反应条件
1: sulfuryl chloride / CH2Cl2 / -78 °C 2: 32 percent / lithium; 4,4'-di-tert-butylbiphenyl / tetrahydrofuran / 1 h / -40 °C View Scheme
参考文献
Tetrahedron, , vol. 62, # 42 p. 9832 - 9839
反应条件
1: 77 percent / sodium iodide; sodium hydride / tetrahydrofuran / 0 - 20 °C 2: sulfuryl chloride / CH2Cl2 / -78 °C 3: 32 percent / lithium; 4,4'-di-tert-butylbiphenyl / tetrahydrofuran / 1 h / -40 °C View Scheme
参考文献
Tetrahedron, , vol. 62, # 42 p. 9832 - 9839
参考文献
Bulletin de la Societe Chimique de France, , p. 4510 - 4518
