2-(4-氯-2-羟基苯氧基)乙酸合成路线 （共 4 条）
反应条件
boron tribromide in dichloromethane
T=20°C; 1 h;
参考文献
Frederick, Raphael; Robert, Severine; Charlier, Caroline; Wouters, Johan; Masereel, Bernard; Pochet, Lionel
Journal of Medicinal Chemistry, 2007 , vol. 50, # 15 p. 3645 - 3650
参考文献
Brown; McCall
Journal of the Chemical Society, 1955 , p. 3681,3683
反应条件
1: 95 percent / Cs2CO3 / dioxane / 4 h / 20 °C
2: 47 percent / BBr3 / CH2Cl2 / 1 h / 20 °C
View Scheme
参考文献
Frederick, Raphael; Robert, Severine; Charlier, Caroline; Wouters, Johan; Masereel, Bernard; Pochet, Lionel
Journal of Medicinal Chemistry, 2007 , vol. 50, # 15 p. 3645 - 3650
反应条件
2: chloroacetic acid; aqueous NaOH
3: aqueous HBr
View Scheme
参考文献
Brown; McCall
Journal of the Chemical Society, 1955 , p. 3681,3683
