2-氰基吡啶-5-硼酸频那酯合成路线 （共 3 条）
反应条件
potassium acetate; palladium dichloride in dichloromethane; dimethyl sulfoxide T=90°C; 6 h;
参考文献
Patrick, Donald A.; Ismail, Mohamed A.; Arafa, Reem K.; Wenzler, Tanja; Zhu, Xiaohua; Pandharkar, Trupti; Jones, Susan Kilgore; Werbovetz, Karl A.; Brun, Reto; Boykin, David W.; Tidwell, Richard R.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 13 p. 5473 - 5494
反应条件
1: 100 percent / I2; aq. NH3 / tetrahydrofuran / 4 h / 20 °C 2: 64 percent / PdCl2(dppf); KOAc / dimethylsulfoxide / 25 h / 80 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 5 p. 1277 - 1281
反应条件
hydrogen; acetic acid; palladium on activated charcoal
T=20°C; 16 h;
参考文献
Wiles, Jason A.; Song, Yongsheng; Wang, Qiuping; Lucien, Edlaine; Hashimoto, Akihiro; Cheng, Jijun; Marlor, Christopher W.; Ou, Yangsi; Podos, Steven D.; Thanassi, Jane A.; Thoma, Christy L.; Deshpande, Milind; Pucci, Michael J.; Bradbury, Barton J.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 5 p. 1277 - 1281
