反应条件
1: (4-amino-2-ethylsulfanylpyrimidin-5-yl)(2,3-difluoro-6-methoxyphenyl)methanone With 3-chloro-benzenecarboperoxoic acid in chloroform T=-15°C; 1 h; 2: 1-(methylsulfonyl)piperidin-4-amine in isopropyl alcohol T=100 - 110°C; 1 h; microwave irradiation;
参考文献
Chu, Xin-Jie; DePinto, Wanda; Bartkovitz, David; So, Sung-Sau; Vu, Binh T.; Packman, Kathryn; Lukacs, Christine; Ding, Qingjie; Jiang, Nan; Wang, Ka; Goelzer, Petra; Yin, Xuefeng; Smith, Melissa A.; Higgins, Brian X.; Chen, Yingsi; Xiang, Qing; Moliterni, John; Kaplan, Gerald; Graves, Bradford; Lovey, Allen; Fotouhi, Nader
Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6549 - 6560
