1-苯基-5-三氟甲基-1H-吡唑-4-羧酸乙酯合成路线 （共 5 条）
反应条件
trans-N,N'-dimethyl-1,2-cyclohexanediamine; copper(l) iodide; potassium carbonate in toluene T=110°C; 24 h;
参考文献
Bolin, David Robert; Cheung, Adrian Wai-Hing; Firooznia, Fariborz; Marcopulos, Nicholas; Qian, Yimin
Patent: US2010/152445 A1, 2010 ;
Location in patent: Page/Page column 8 ;
反应条件
pyridine; copper diacetate in N,N-dimethyl-formamide T=20°C; 24 h;
参考文献
Wu, Zhibing; Hu, Deyu; Kuang, Jiqing; Cai, Hua; Wu, Shixi; Xue, Wei
Molecules, 2012 , vol. 17, # 12 p. 14205 - 14218
反应条件
1: acetic anhydride / 12 h / 120 °C 2: hydrazine hydrate / methanol / 3 h / 80 °C 3: copper diacetate; pyridine / N,N-dimethyl-formamide / 24 h / 20 °C View Scheme
参考文献
Molecules, , vol. 17, # 12 p. 14205 - 14218
反应条件
1: hydrazine hydrate / methanol / 3 h / 80 °C 2: copper diacetate; pyridine / N,N-dimethyl-formamide / 24 h / 20 °C View Scheme
参考文献
Molecules, , vol. 17, # 12 p. 14205 - 14218
反应条件
lithium hydroxide hydrate in tetrahydrofuran T=70°C; pH=5; 2 h;
参考文献
Wu, Zhibing; Hu, Deyu; Kuang, Jiqing; Cai, Hua; Wu, Shixi; Xue, Wei
Molecules, 2012 , vol. 17, # 12 p. 14205 - 14218
