1: potassium carbonate / N,N-dimethyl-formamide / 24 h / 20 °C
2: n-butyllithium / tetrahydrofuran / 2 h / -70 °C
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参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BRENNEMAN, Jehrod Burnett; GINN, John; LOWE, Michael D.; SARKO, Christopher Ronald; TASBER, Edward S.; ZHANG, Zhonghua
Patent: US2014/73629 A1, 2014 ;
1: potassium carbonate / N,N-dimethyl-formamide / 24 h / 20 °C
2: N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile / tetrachloromethane / 12 h / |Reflux
View Scheme
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BRENNEMAN, Jehrod Burnett; GINN, John; LOWE, Michael D.; SARKO, Christopher Ronald; TASBER, Edward S.; ZHANG, Zhonghua
Patent: US2014/73629 A1, 2014 ;
