3-溴-4-硝基-1H-吲唑合成路线 （共 4 条）
反应条件
bromine; sodium acetate; acetic acid in chloroform T=25°C; 5.5 h;
参考文献
ARRAY BIOPHARMA INC.; BOYS, Mark Laurence; DELISLE, Robert Kirk; HICKEN, Erik James; KENNEDY, April L.; MARESKA, David A.; MARMSATER, Fredrik P.; MUNSON, Mark C.; NEWHOUSE, Brad; RAST, Bryson; RIZZI, James P.; RODRIGUEZ, Martha E.; TOPALOV, George T.; ZHAO, Qian
Patent: WO2012/82689 A1, 2012 ;
Location in patent: Page/Page column 58 ;
WO 2012/082689 A1
反应条件
1: sodium nitrite / water; acetic acid 2: N-bromosuccinmide / acetonitrile / 1.5 h / Reflux View Scheme
参考文献
Synthetic Communications, , vol. 41, # 7 p. 999 - 1005
反应条件
tin(ll) chloride T=60°C;
参考文献
Abbassi, Najat; Chicha, Hakima; Rakib, El Mostapha; Hannioui, Abdellah; Alaoui, Mdaghri; Hajjaji, Abdelouahed; Geffken, Detlef; Aiello, Cinzia; Gangemi, Rosaria; Rosano, Camillo; Viale, Maurizio
European Journal of Medicinal Chemistry, 2012 , vol. 57, p. 240 - 249
反应条件
tin(ll) chloride
T=60°C;
参考文献
Abbassi, Najat; Chicha, Hakima; Rakib, El Mostapha; Hannioui, Abdellah; Alaoui, Mdaghri; Hajjaji, Abdelouahed; Geffken, Detlef; Aiello, Cinzia; Gangemi, Rosaria; Rosano, Camillo; Viale, Maurizio
European Journal of Medicinal Chemistry, 2012 , vol. 57, p. 240 - 249
