3-氟-2-甲氧基苯甲醛合成路线 （共 17 条）
反应条件
caesium carbonate in N,N-dimethyl-formamide T=20°C; 2 h; Inert atmosphere;
参考文献
ELI LILLY AND COMPANY
Patent: WO2009/140448 A1, 2009 ;
Location in patent: Page/Page column 38-39 ;
反应条件
potassium carbonate in acetone
参考文献
ELI LILLY AND COMPANY
Patent: WO2004/43904 A1, 2004 ;
Location in patent: Page 29 ;
WO 2004/043904 A1
反应条件
1: 47 percent / liquid nitrogen dioxide / pentane / 35 min, 0 deg C then 20 min, room temperature 3: 94 percent / hydrogen / 5percent Pd/C / ethyl acetate / 24 h View Scheme
参考文献
Bulletin de la Societe Chimique de France, , vol. 2, # 3-4 p. 175 - 178
反应条件
1: 98 percent / liquide nitrogen dioxide / pentane / 35 min, 0 deg C then 20 min, room temperature 3: 86 percent / hydrogen, KOH / 5percent Pd/C / methanol / 1 h / 60004.8 - 75005.9 Torr View Scheme
参考文献
Bulletin de la Societe Chimique de France, , vol. 2, # 3-4 p. 175 - 178
反应条件
2: 94 percent / hydrogen / 5percent Pd/C / ethyl acetate / 24 h View Scheme
参考文献
Bulletin de la Societe Chimique de France, , vol. 2, # 3-4 p. 175 - 178
反应条件
1: 98.5 percent / hydrogen / 5percent Pd/C / ethyl acetate / 24 h / 760 Torr 2: 2., HBr, CuBr 3: 98 percent / liquide nitrogen dioxide / pentane / 35 min, 0 deg C then 20 min, room temperature 5: 86 percent / hydrogen, KOH / 5percent Pd/C / methanol / 1 h / 60004.8 - 75005.9 Torr View Scheme
参考文献
Bulletin de la Societe Chimique de France, , vol. 2, # 3-4 p. 175 - 178
反应条件
1: 2., HBr, CuBr 2: 98 percent / liquide nitrogen dioxide / pentane / 35 min, 0 deg C then 20 min, room temperature 4: 86 percent / hydrogen, KOH / 5percent Pd/C / methanol / 1 h / 60004.8 - 75005.9 Torr View Scheme
参考文献
Bulletin de la Societe Chimique de France, , vol. 2, # 3-4 p. 175 - 178
反应条件
1: 94 percent / hydrogen / 5percent Pd/C / ethyl acetate / 24 h View Scheme
参考文献
Bulletin de la Societe Chimique de France, , vol. 2, # 3-4 p. 175 - 178
反应条件
2: 86 percent / hydrogen, KOH / 5percent Pd/C / methanol / 1 h / 60004.8 - 75005.9 Torr View Scheme
参考文献
Bulletin de la Societe Chimique de France, , vol. 2, # 3-4 p. 175 - 178
反应条件
1: 86 percent / hydrogen, KOH / 5percent Pd/C / methanol / 1 h / 60004.8 - 75005.9 Torr View Scheme
参考文献
Bulletin de la Societe Chimique de France, , vol. 2, # 3-4 p. 175 - 178
