反应条件
1: 1.) hydroxylamine hydrochloride, sodium acetate, 2.) aq. hydrochloric acid / 1.) water, ethanol, 80 deg C, 3 h, 2.) ethanol, reflux, 30 min
2: sodium, isopropanol
3: hydrogen chloride / 48 h / Ambient temperature
4: 33 percent / o-tolylmagnesium bromide / diethyl ether; CH2Cl2 / 48 h / Ambient temperature
View Scheme
参考文献
Shibuya, Masayuki; Kubota, Seiju
Heterocycles, 1980 , vol. 14, # 5 p. 601 - 609