1: 1.) LDA / 1.) THF, 0 deg C to 25 deg C, 1 h, 2.) THF, -50 deg C to 25 deg C 2: 89 percent / AcOH / tetrahydrofuran; H2O / 4 h / 40 °C View Scheme

1: 65 percent / LiH / tetrahydrofuran / 4 h / Heating 2: 72 percent / aq. AcOH / 1 h / 80 °C View Scheme