sodium tetrahydroborate in ethanol; toluene T=0 - 20°C;

lithium aluminium tetrahydride in diethyl ether 5 h; Heating;

1: 3-methyl thiophene With 2,2,6,6-tetramethyl-piperidine; isopropylmagnesium chloride in tetrahydrofuran T=66°C; Inert atmosphere; 2: formaldehyd in tetrahydrofuran T=0°C; 2 h; Inert atmosphere; 3: With hydrogenchloride in tetrahydrofuran; water pH=5; regioselective reaction;

lithium aluminium tetrahydride in diethyl ether Yield given;

lithium in various solvent(s)

chromium(VI) oxide in pyridine 2 h; Ambient temperature;