1,2,3,4-四氢-1-氧代-2-萘羧酸甲酯合成路线 （共 17 条）
参考文献
Ito, Yoshihiko; Nakajo, Eiji; Sho, Katsuhiko; Saegusa, Takeo
Synthesis, 1985 , # 6/7 p. 698 - 699
反应条件
lithium diisopropyl amide
1.) THF, -78 deg C, 2.) THF; Multistep reaction;
参考文献
Kees, Kenneth L.; Caggiano, Thomas J.; Steiner, Kurt E.; Fitzgerald, John J.; Kates, Michael J.; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 4 p. 617 - 628
反应条件
water; oxalic acid
10 h; Ambient temperature;
参考文献
Ito, Yoshihiko; Nakajo, Eiji; Saegusa, Takeo
Tetrahedron Letters, 1984 , vol. 25, # 45 p. 5139 - 5142
参考文献
Kraus, George A.; Chen, Li
Tetrahedron Letters, 1991 , vol. 32, # 49 p. 7151 - 7154
反应条件
2: pyridine / 0 °C
3: toluene / 100 °C
4: 69 percent / DBU, LiCl / acetonitrile / Ambient temperature
View Scheme
参考文献
Nangia, A.; Rao, P. Bheema
Tetrahedron Letters, 1992 , vol. 33, # 17 p. 2375 - 2378
反应条件
1: 66 percent / NaOMe / methanol / 10 h / Heating
2: 85 percent / Raney Ni (W2) / ethanol / 4 h / Heating
3: 80 percent / 10 percent Pd/C / 1,2-dichloro-benzene / 48 h / Heating
View Scheme
参考文献
Chakrabarty, Manas; Sarkar, Sandipan; Harigaya, Yoshihiro
Synthesis, 2003 , # 15 p. 2292 - 2294
反应条件
1: 1.) NaBH4 / 1.) methanol, 0 deg C, 30-45 min; 2.) methanol, rt, 3-4 h
2: 82 percent / p-toluenesulfonic acid monohydrate, hydroquinone / benzene / Heating
View Scheme
参考文献
Verbel, Joel; Carrie, Robert
Bulletin de la Societe Chimique de France, 1982 , vol. 2, # 3-4 p. 116 - 124
