Γ-O-十八烷基-L-Α-溶血卵磷脂合成路线 （共 45 条）
反应条件
potassium carbonate in methanol 3 h; Ambient temperature;
参考文献
Hirth; Barner
Helvetica Chimica Acta, 1982 , vol. 65, # 3 p. 1059 - 1084
反应条件
1: H2 / 5percent Pd/C / tetrahydrofuran / 0.25 h 2: 68.7 percent / pyridine / 72 h / Ambient temperature 3: 98.6 percent / NaH / dimethylformamide / 2 h / 80 °C 4: 88 percent / 1N HCl / dioxane / 1.5 h / 90 °C 5: 79 percent / phosphorus oxychloride, Et3N, pyridine / CHCl3 / Ambient temperature 6: 100 percent / H2 / PdO / methanol; H2O / 1 h / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 65, # 3 p. 1059 - 1084
反应条件
1: 81.5 percent / 1N HCl / dioxane / 1 h / Heating 2: t-BuOK / tetrahydrofuran / Ambient temperature 3: dimethylformamide / 80 °C 4: H2 / 5percent Pd/C / tetrahydrofuran / 0.25 h 5: 68.7 percent / pyridine / 72 h / Ambient temperature 6: 98.6 percent / NaH / dimethylformamide / 2 h / 80 °C 7: 88 percent / 1N HCl / dioxane / 1.5 h / 90 °C 8: 79 percent / phosphorus oxychloride, Et3N, pyridine / CHCl3 / Ambient temperature 9: 100 percent / H2 / PdO / methanol; H2O / 1 h / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 65, # 3 p. 1059 - 1084
反应条件
1: dimethylformamide / 80 °C 2: H2 / 5percent Pd/C / tetrahydrofuran / 0.25 h 3: 68.7 percent / pyridine / 72 h / Ambient temperature 4: 98.6 percent / NaH / dimethylformamide / 2 h / 80 °C 5: 88 percent / 1N HCl / dioxane / 1.5 h / 90 °C 6: 79 percent / phosphorus oxychloride, Et3N, pyridine / CHCl3 / Ambient temperature 7: 100 percent / H2 / PdO / methanol; H2O / 1 h / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 65, # 3 p. 1059 - 1084
反应条件
1: t-BuOK / tetrahydrofuran / Ambient temperature 2: dimethylformamide / 80 °C 3: H2 / 5percent Pd/C / tetrahydrofuran / 0.25 h 4: 68.7 percent / pyridine / 72 h / Ambient temperature 5: 98.6 percent / NaH / dimethylformamide / 2 h / 80 °C 6: 88 percent / 1N HCl / dioxane / 1.5 h / 90 °C 7: 79 percent / phosphorus oxychloride, Et3N, pyridine / CHCl3 / Ambient temperature 8: 100 percent / H2 / PdO / methanol; H2O / 1 h / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 65, # 3 p. 1059 - 1084
反应条件
2: H2 / Pd-C / ethanol; tetrahydrofuran / 48 h / 2942.03 Torr / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 31, # 5 p. 699 - 702
反应条件
1: p-TsOH 3: H2 / Pd-C / ethanol; tetrahydrofuran / 48 h / 2942.03 Torr / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 31, # 5 p. 699 - 702
反应条件
1: 68.7 percent / pyridine / 72 h / Ambient temperature 2: 98.6 percent / NaH / dimethylformamide / 2 h / 80 °C 3: 88 percent / 1N HCl / dioxane / 1.5 h / 90 °C 4: 79 percent / phosphorus oxychloride, Et3N, pyridine / CHCl3 / Ambient temperature 5: 100 percent / H2 / PdO / methanol; H2O / 1 h / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 65, # 3 p. 1059 - 1084
反应条件
1: 68.5 percent / KOH / methanol; H2O / 0.5 h / Heating 2: 68.7 percent / pyridine / 72 h / Ambient temperature 3: 98.6 percent / NaH / dimethylformamide / 2 h / 80 °C 4: 88 percent / 1N HCl / dioxane / 1.5 h / 90 °C 5: 79 percent / phosphorus oxychloride, Et3N, pyridine / CHCl3 / Ambient temperature 6: 100 percent / H2 / PdO / methanol; H2O / 1 h / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 65, # 3 p. 1059 - 1084
反应条件
1: 98.6 percent / NaH / dimethylformamide / 2 h / 80 °C 2: 88 percent / 1N HCl / dioxane / 1.5 h / 90 °C 3: 79 percent / phosphorus oxychloride, Et3N, pyridine / CHCl3 / Ambient temperature 4: 100 percent / H2 / PdO / methanol; H2O / 1 h / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 65, # 3 p. 1059 - 1084
