N-(4-氯-苯基)-N,N-二甲基-1,2-乙二胺合成路线 （共 5 条）
反应条件
1: in water
T=150°C; 0.333333 h; Microwave irradiation;
2: With sodium hydrogencarbonate in water
chemoselective reaction;
参考文献
Marzaro, Giovanni; Guiotto, Adriano; Chilin, Adriana
Green Chemistry, 2009 , vol. 11, # 6 p. 774 - 776
反应条件
in N-methyl-acetamide; methanol; dichloromethane; toluene
参考文献
E. R. Squibb and Sons, Inc.
Patent: US5374643 A1, 1994 ;
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
18 h;
参考文献
Lehmann, Fredrik; Pettersen, Anna; Currier, Erika A.; Sherbukhin, Vladimir; Olsson, Roger; Hacksell, Uli; Luthman, Kristina
Journal of Medicinal Chemistry, 2006 , vol. 49, # 7 p. 2232 - 2240
反应条件
1: Et3N / tetrahydrofuran / 2 h
2: tetrahydrofuran / 18 h
3: 5.17 g / LiAlH4 / tetrahydrofuran / 18 h
View Scheme
参考文献
Lehmann, Fredrik; Pettersen, Anna; Currier, Erika A.; Sherbukhin, Vladimir; Olsson, Roger; Hacksell, Uli; Luthman, Kristina
Journal of Medicinal Chemistry, 2006 , vol. 49, # 7 p. 2232 - 2240
反应条件
1: tetrahydrofuran / 18 h
2: 5.17 g / LiAlH4 / tetrahydrofuran / 18 h
View Scheme
参考文献
Lehmann, Fredrik; Pettersen, Anna; Currier, Erika A.; Sherbukhin, Vladimir; Olsson, Roger; Hacksell, Uli; Luthman, Kristina
Journal of Medicinal Chemistry, 2006 , vol. 49, # 7 p. 2232 - 2240
