74497-02-2合成路线 （共 11739 条）
参考文献
Gardner et al.
Journal of the Chemical Society, 1949 , p. 780
Full Text Show Details
Gen. Aniline and Film Corp.
Patent: US2342493 , 1940 ;
反应条件
1: 1-(4-chlorophenyl)pent-2-yne-1,4-diol With ruthenium(II)-carbonyl-tris(triphenylphosphine) dihydride; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in toluene
0.5 h; Inert atmosphereReflux;
2: aniline in toluene
23.5 h; Inert atmosphereReflux;
参考文献
Pridmore, Simon J.; Slatford, Paul A.; Taylor, James E.; Whittlesey, Michael K.; Williams, Jonathan M.J.
Tetrahedron, 2009 , vol. 65, # 44 p. 8981 - 8986
反应条件
9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in toluene
24 h; Heating; Title compound not separated from byproducts.;
参考文献
Pridmore, Simon J.; Slatford, Paul A.; Daniel, Aurelie; Whittlesey, Michael K.; Williams, Jonathan M.J.
Tetrahedron Letters, 2007 , vol. 48, # 29 p. 5115 - 5120
反应条件
1: carbon monoxide; (4-Chlorophenyl)-boronic acid; methyl vinyl ketone With RhH(CO)(triphenylphosphine)3 in methanol
T=80°C; P=15001.2 Torr; 18 h;
2: aniline With iodine in tetrahydrofuran
T=40°C; Paal-Knorr cyclization;
参考文献
Chochois, Helene; Sauthier, Mathieu; Maerten, Eddy; Castanet, Yves; Mortreux, Andre
Tetrahedron, 2006 , vol. 62, # 50 p. 11740 - 11746
反应条件
phenylammonium bromide in ethanol
3 h; Heating;
参考文献
Cerreto; Villa; Retico; Scalzo
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 7 p. 701 - 708
反应条件
1: 1-(4-chlorophenyl)pent-2-yne-1,4-diol With ruthenium(II)-carbonyl-tris(triphenylphosphine) dihydride; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in toluene
0.5 h; Inert atmosphereReflux;
2: aniline in toluene
23.5 h; Inert atmosphereReflux;
参考文献
Pridmore, Simon J.; Slatford, Paul A.; Taylor, James E.; Whittlesey, Michael K.; Williams, Jonathan M.J.
Tetrahedron, 2009 , vol. 65, # 44 p. 8981 - 8986
反应条件
9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in toluene
24 h; Heating; Title compound not separated from byproducts.;
参考文献
Pridmore, Simon J.; Slatford, Paul A.; Daniel, Aurelie; Whittlesey, Michael K.; Williams, Jonathan M.J.
Tetrahedron Letters, 2007 , vol. 48, # 29 p. 5115 - 5120
反应条件
in chloroform
T=50°C; 0.5 h;
参考文献
Rawling, Tristan; McDonagh, Andrew M.; Tattam, Bruce; Murray, Michael
Tetrahedron, 2012 , vol. 68, # 30 p. 6065 - 6070
反应条件
1: aniline With hydrogenchloride; sodium nitrite in water
T=0 - 5°C; Cooling with ice;
2: potassium acetoacetate With hydrogenchloride in water
Cooling with ice;
参考文献
Aljahdali; El-Sherif, Ahmed A.
Inorganica Chimica Acta, 2013 , vol. 407, p. 58 - 68
参考文献
ICI
Patent: US1972918 , 1932 ;
Full Text Show Details
Naugatuck Chem. Co.
Patent: US1901582 , 1931 ;
Full Text Show Details
U.S. Rubber Co.
Patent: US2010059 , 1931 ;
Full Text Show Details
U.S. Rubber Co.
Patent: US1996011 , 1932 ;
