74497-02-2合成路线 （共 11739 条）
反应条件
sodium; copper
1.) 180 deg C, 3 h, 2.) 230 deg C, 30 h;; Yield given. Multistep reaction;
参考文献
Shein, S. M.; Rusov, V. P.; Sokolenko, V. I.
Journal of Organic Chemistry USSR (English Translation), 1980 , vol. 16, p. 2014 - 2016
Zhurnal Organicheskoi Khimii, 1980 , vol. 16, # 11 p. 2356 - 2358
参考文献
Bayer and Co.
Patent: DE80977 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 4, p. 83
反应条件
1: acetic acid / 20 h / 80 °C / |Inert atmosphere
2: palladium diacetate; copper diacetate; potassium carbonate / N,N-dimethyl-formamide / 15 h / 80 °C / |Inert atmosphere
3: sodium hydroxide / tetrahydrofuran / 2 h / 20 °C
4: sodium hydroxide / water; ethanol / 15 h / 80 °C
View Scheme
参考文献
Zhang, Xiang; Zhang-Negrerie, Daisy; Deng, Jun; Du, Yunfei; Zhao, Kang
Journal of Organic Chemistry, 2013 , vol. 78, # 24 p. 12750 - 12759
反应条件
1: diethyl ether / beim Schuetteln in der Kaelte
2: concentrated hydrochloric acid
View Scheme
参考文献
Banti
Gazzetta Chimica Italiana, 1929 , vol. 59, p. 824
反应条件
potassium hydroxide; ethanol
参考文献
Banti
Gazzetta Chimica Italiana, 1929 , vol. 59, p. 824
反应条件
T=160°C; Verseifen des erhaltenen Estergemisches;
参考文献
Iwakura,Y. et al.
Tetrahedron, 1968 , vol. 24, p. 575 - 583
反应条件
triethylamine in ethanol
T=140°C; 0.25 h; Microwave irradiation;
参考文献
Felts, Andrew S.; Saleh, Sam A.; Le, Uyen; Rodriguez, Alice L.; Weaver, C. David; Conn, P. Jeffrey; Lindsley, Craig W.; Emmitte, Kyle A.
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 23 p. 6623 - 6626
反应条件
1: 1.) conc. HCl, NaNO2 2.) pyridine / 1.) water 2.) 0 deg C
2: BF3 / acetic acid / 0.17 h
3: 0.15 g / 30percent H2O2 / acetic acid / 96 h / Ambient temperature
View Scheme
参考文献
Atallah, Raja H.; Nazer, Musa Z.
Tetrahedron, 1982 , vol. 38, # 12 p. 1793 - 1796
反应条件
1: dichloromethane / 1 h / 20 °C
2: nitric acid; acetic acid / 0.5 h / 0 °C
3: hydrogenchloride / water / 2 h / |Reflux
4: potassium carbonate; copper(l) iodide / N,N-dimethyl-formamide / 4 h / 120 °C
View Scheme
参考文献
Yu, Yongguo; Wu, Jianbo; Lei, Fan; Chen, Lei; Wan, Weili; Hai, Li; Guan, Mei; Wu, Yong
Letters in Drug Design and Discovery, 2013 , vol. 10, # 4 p. 369 - 373
反应条件
triethylamine; benzenesulfonyl chloride in acetone
T=20 - 23°C; 0.0833333 h;
参考文献
Urbanski, Jerzy; Manek, Maria Beata
Polish Journal of Chemistry, 1983 , vol. 57, # 4/5/6 p. 603 - 605
