74497-02-2合成路线 （共 11739 条）
反应条件
2-picoline; sulfur dioxide; zinc in N,N-dimethyl-formamide
0.5 h;
参考文献
Wakselman, Claude; Tordeux, Marc
Journal of the Chemical Society, Chemical Communications, 1987 , p. 1701 - 1703
反应条件
T=100°C; 1 h; Heating;
参考文献
Scartoni; Tognetti
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 5 p. 1499 - 1503
反应条件
cupric nitrate trihydrate supported on K 10 montmorillonite clay; nitric acid in tetrachloromethane
2.5 h; Ambient temperature;
参考文献
Gigante, Barbara; Prazeres, Angela O.; Marcelo-Curto, Maria J.; Cornelis, Andre; Laszlo, Pierre
Journal of Organic Chemistry, 1995 , vol. 60, # 11 p. 3445 - 3447
参考文献
Abed,N.M.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1976 , vol. 14, p. 428 - 429
参考文献
Winkelmann
Journal fuer Praktische Chemie (Leipzig), 1927 , vol. <2> 115, p. 293
反应条件
1: 88 percent / methanol / Heating
2: 63 percent / NaN3 / dimethylformamide / 115 - 120 °C
View Scheme
参考文献
Chardonnens; Heinrich
Helvetica Chimica Acta, 1940 , vol. 23, p. 1399,1406
反应条件
potassium carbonate in tetrahydrofuran
3 h; Heating;
参考文献
Moraczewski, Alexei L.; Banaszynski, Laura A.; From, Aaron M.; White, Courtney E.; Smith, Bradley D.
Journal of Organic Chemistry, 1998 , vol. 63, # 21 p. 7258 - 7262
反应条件
acetic acid in isopropyl alcohol
Cooling with iceReflux;
参考文献
The United States of America as Represented by the Secretary of the Army; Walz, Andrew J; Hsu, Fu-Lian
Patent: US8742111 B1, 2014 ;
Location in patent: Page/Page column 5; 6 ;
反应条件
1: acetic acid / isopropyl alcohol / |Cooling with ice; |Reflux
2: sulfuric acid; trifluoroacetic acid / 16 h / 45 - 50 °C / |Inert atmosphere
View Scheme
参考文献
The United States of America as Represented by the Secretary of the Army; Walz, Andrew J; Hsu, Fu-Lian
Patent: US8742111 B1, 2014 ;
反应条件
1: 81 percent / acetic acid / 0.5 h / T < 40 deg C
2: 100 percent / CH2Cl2 / 0.5 h / 20 - 30 °C
3: 60 percent / aq. HCl / 1 h / Heating
4: 82 percent / aq. sodium hydroxide / 18.5 h / 225 °C
View Scheme
参考文献
Feldman; Brackeen
Journal of Organic Chemistry, 1990 , vol. 55, # 13 p. 4207 - 4209
