74497-02-2合成路线 （共 11739 条）
反应条件
4-(N,N-dimethlyamino)pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane
T=20°C;
参考文献
BIOTA SCIENTIFIC MANAGEMENT PTY LTD; DRAFFAN, Alistair George; HUFTON, Richard; POOL, Brett Raymond; HARDING, Michael; JAHANGIRI, Saba; JEYNES, Tyrone Pieter; CIANCI, Julia; FREY, Barbara
Patent: WO2011/153588 A1, 2011 ;
Location in patent: Page/Page column 40 ;
WO 2011/153588 A1
反应条件
in 1,4-dioxane
1 h; Heating;
参考文献
Cativiela, C; Fernandez, J.; Melendez, E.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1093 - 1097
反应条件
4-methyl-morpholine; isobutyl chloroformate
1.) THF, -10 deg C, 30 min, 2.) RT, 18 h; Yield given. Multistep reaction;
参考文献
Vinick, Fredric J.; Saccomano, Nicholas A.; Koe, B. Kenneth; Nielsen, Jann A.; Williams, Ian H.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 86 - 89
反应条件
sulfuric acid; silica gel
T=80°C; 4 h;
参考文献
Salehi, Peyman; Dabiri, Minoo; Zolfigol, Mohammad Ali; Baghbanzadeh, Mostafa
Tetrahedron Letters, 2005 , vol. 46, # 41 p. 7051 - 7053
反应条件
in butan-1-ol
6 h; Heating;
参考文献
Essawy, A.; El-Hashash, M. A.; El-Gendy, A. M.; Hamad, M. M. M.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 6 p. 593 - 595
反应条件
alum
0.1 h; Microwave irradiationneat (no solvent);
参考文献
Mohammadi, Ali A.; Sadat Hossini
Chinese Journal of Chemistry, 2011 , vol. 29, # 9 p. 1982 - 1984
反应条件
phosphorus trichoride
参考文献
Kacker; Zaheer
Journal of the Indian Chemical Society, 1951 , vol. 28, p. 344
参考文献
Zincke
Journal fuer Praktische Chemie (Leipzig), 1912 , vol. <2> 85, p. 219
参考文献
Schoepf; Hartmann; Koch
Chemische Berichte, 1936 , vol. 69, p. 2766,2768 Anm.6
Full Text Show Details
Baumgarten
Chemische Berichte, 1932 , vol. 65, p. 1637,1642
参考文献
Kuhn,R.; Teller,E.
Justus Liebigs Annalen der Chemie, 1968 , vol. 715, p. 106 - 121
