74497-02-2合成路线 （共 11739 条）
参考文献
Masuda
Yakugaku Zasshi, 1934 , vol. 54, p. 25,40, 41
Proceedings of the Imperial Academy (Tokyo), 1933 , vol. 9, p. 599
反应条件
triethylamine in tetrahydrofuran
72 h;
参考文献
Katritzky, Alan R.; Ledoux, Stephane; Witek, Rachel M.; Nair, Satheesh K.
Journal of Organic Chemistry, 2004 , vol. 69, # 9 p. 2976 - 2982
参考文献
Jacobson
Justus Liebigs Annalen der Chemie, 1922 , vol. 427, p. 219
参考文献
Zincke; Jaenke
Chemische Berichte, 1888 , vol. 21, p. 547
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Goldschmidt; Bardach
Chemische Berichte, 1892 , vol. 25, p. 1369
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Nietzki
Chemische Berichte, 1877 , vol. 10, p. 664,666
参考文献
Fukami; Yokojima
J.Soc.chem.Ind.Japan Spl., vol. 31, p. 34 B
Chem. Zentralbl., 1928 , vol. 99, # I p. 2248
参考文献
Shell Devel. Co.
Patent: US2566815 , 1947 ;
反应条件
1: aniline With hydrogenchloride; sodium nitrite
T=0 - 10°C;
2: dimethyl amine With sodium carbonate in water
0.5 h; cooling;
参考文献
Manolov, Ilia; Machulla; Momekov
Pharmazie, 2006 , vol. 61, # 6 p. 511 - 516
反应条件
(i) EtOH, (ii) HCl; Multistep reaction;
参考文献
Becher,J. et al.
Tetrahedron, 1979 , vol. 35, p. 869 - 873
反应条件
4-(N,N-dimethlyamino)pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in N,N-dimethyl-formamide
T=25°C; 14 h;
参考文献
THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION; COLORADO STATE UNIVERSITY RESEARCH FOUNDATION
Patent: WO2005/7625 A2, 2005 ;
Location in patent: Page 38-39 ;
反应条件
triethylamine in dichloromethane
T=20°C; 5 h;
参考文献
Zhou, Linna; Stewart, Gavin; Rideau, Emeline; Westwood, Nicholas J.; Smith, Terry K.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 3 p. 796 - 806
