74497-02-2合成路线 （共 11739 条）
反应条件
1: Et3N / CH2Cl2 / 0.08 h / Ambient temperature
2: Sn, 6 N HCl / tetrahydrofuran / 1 h / 50 °C
3: pyridine / 1.5 h / 60 °C
View Scheme
参考文献
Ogata, Masaru; Matsumoto, Hiroshi; Shimizu, Sumio; Kida, Shiro; Wada, Toru; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 3 p. 417 - 423
反应条件
triethylamine in dichloromethane
0.166667 h; Ambient temperature; Yield given;
参考文献
Ogata, Masaru; Matsumoto, Hiroshi; Shimizu, Sumio; Kida, Shiro; Wada, Toru; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 3 p. 417 - 423
参考文献
Prodanchuk, N. G.; Megera, I. V.; Patratii, V. K.
Pharmaceutical Chemistry Journal, 1984 , vol. 18, # 2 p. 108 - 110
Khimiko-Farmatsevticheskii Zhurnal, 1984 , vol. 18, # 2 p. 173 - 175
反应条件
1: 94 percent
2: 93 percent / benzene / 0.17 h / Ambient temperature
View Scheme
参考文献
Suvorova, I. V.; Stadnichuk, M. D.
J. Gen. Chem. USSR (Engl. Transl.), 1984 , vol. 54, # 1 p. 132 - 139,116 - 122
参考文献
Graf,R.
Chemische Berichte, 1963 , vol. 96, p. 56 - 67
反应条件
in diethyl ether
0.0833333 h; Yield given;
参考文献
Brzezinski, Bogumil
Polish Journal of Chemistry, 1983 , vol. 57, # 1-3 p. 249 - 252
反应条件
1.5 h; Heating; Title compound not separated from byproducts;
参考文献
Saeed, Ali A. H.
Journal of Chemical & Engineering Data, 1984 , vol. 29, # 3 p. 358 - 361
反应条件
in ethanol
0.05 h; Heating;
参考文献
Thiel, W.; Mayer, R.
Journal fuer Praktische Chemie (Leipzig), 1989 , vol. 331, # 2 p. 243 - 262
反应条件
sulfur; triethylamine
1.) DMF, 2.) EtOH, reflux, 4 h; Yield given. Multistep reaction;
参考文献
Thiel, W.; Mayer, R.
Journal fuer Praktische Chemie (Leipzig), 1989 , vol. 331, # 2 p. 243 - 262
参考文献
Milligan; Swan
Journal of the Chemical Society, 1959 , p. 2969,2976
