2-(氯甲基)-4,6-二甲基嘧啶合成路线 （共 11 条）
反应条件
trichlorophosphate in chloroform 3 h; Heating;
参考文献
Sakamoto, Takao; Tanji, Ken-Ichi; Niitsuma, Setsuko; Ono, Takayasu; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 11 p. 3362 - 3368
反应条件
1: 93 percent / cc. H2SO4, (NH4)2S2O8 / H2O / 5 h / Heating 2: 90 percent / POCl3 / CHCl3 / 3 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 28, # 11 p. 3362 - 3368
反应条件
1: H2O / 20 h / 100 °C / sealed tube 2: 69 percent Spectr. / phosphoryl chloride / dioxane View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 31, # 12 p. 4533 - 4538
反应条件
trichlorophosphate in 1,4-dioxane Yield given. Yields of byproduct given;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 31, # 12 p. 4533 - 4538
反应条件
trichlorophosphate in 1,4-dioxane
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 31, # 12 p. 4533 - 4538
反应条件
1: sodium tetrahydroborate; ethanol / 0 - 20 °C / |Inert atmosphere 2: trichlorophosphate / chloroform / 0 - 65 °C / |Inert atmosphere View Scheme
反应条件
1: palladium(II) dichloride bis[bis(diphenylphosphine)ferrocene]; triethylamine / acetonitrile / 20 - 100 °C / |Inert atmosphere 2: sodium tetrahydroborate; ethanol / 0 - 20 °C / |Inert atmosphere 3: trichlorophosphate / chloroform / 0 - 65 °C / |Inert atmosphere View Scheme
反应条件
in ethanol; water 1.5 h; Heating;
参考文献
Sakamoto, Takao; Tanji, Ken-Ichi; Niitsuma, Setsuko; Ono, Takayasu; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 11 p. 3362 - 3368
反应条件
1: 78 percent / benzyltriethylammonium chloride / benzene / 22 h / 70 °C
2: 86 percent / 30 percent H2O2 / acetone / 168 h / Ambient temperature
3: 81 percent / I2 / 6 h / Heating
4: cc. HCl / aq. ethanol / 1 h / Heating
View Scheme
参考文献
Sakamoto, Takao; Tanji, Ken-Ichi; Niitsuma, Setsuko; Ono, Takayasu; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 11 p. 3362 - 3368
参考文献
Sakamoto, Takao; Yoshizawa, Hiroshi; Kaneda, Sohichi; Hama, Yoshiaki; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4533 - 4538
