1: oxalic acid monoethyl ester chloride With AlCl3, aluminium chloride in dichloromethane T=0 - 2°C; 0.666667 h; 2: cyclopropyl phenyl sulphide in dichloromethane T=0 - 20°C; 2.75 h;

1: oxalic acid monoethyl ester chloride With AlCl3, aluminium chloride in dichloromethane T=0 - 2°C; 0.666667 h; 2: cyclopropyl phenyl sulphide in dichloromethane T=0 - 20°C;

1: chlorooxo ethylacetate With AlCl3, aluminium chloride in dichloromethane T=0°C; 0.75 h; Inert atmosphere; 2: cyclopropyl phenyl sulphide in dichloromethane T=25°C; 2 h;

1: 4-THP-CH2PPh3I With lithium hexamethyldisilazane in tetrahydrofuran T=0 - 20°C; Wittig olefination; 3 h; Large scale reaction; 2: ethyl 2-(4-(cyclopropylthio)phenyl)-2-oxoacetate in tetrahydrofuran T=0 - 20°C; Wittig olefination; Large scale reaction; Further stages;

1.1: lithium hexamethyldisilazane / tetrahydrofuran / 3 h / 0 - 20 °C / Large scale reaction 1.2: 0 - 20 °C / Large scale reaction 2.1: bis(norbornadiene)rhodium(I) tetrafluoroborate; (R)-(S)-MOD-Mandyphos; hydrogen; triethylamine / methanol / 4 h / 20 °C / 4380.18 Torr / Inert atmosphere; Autoclave View Scheme

1: With sodium hydroxide; water in toluene T=50 - 60°C; 4 h; 2: With hydrogenchloride in water; toluene T=20°C; pH=7; 18 h;

3-chloro-benzenecarboperoxoic acid in dichloromethane T=5 - 20°C; 2 h;