反应条件
1: 91 percent / 0.5 h / 145 °C
2: 1.) (COCl)2, DMSO, 2.) DIEA / 1.) CH2Cl2, -45 deg C, 15 min, 2.) CH2Cl2, -30 deg C, 30 min
View Scheme
参考文献
Jackson, Delwin S.; Fraser, Stephanie A.; Ni, Li-Ming; Kam, Chih-Min; Winkler, Ulrike; Johnson, David A.; Froelich, Christopher J.; Hudig, Dorothy; Powers, James C.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 13 p. 2289 - 2301