双环[3.3.0]辛烷-3,7-二酮合成路线 （共 3 条）
反应条件
lithium aluminium tetrahydride; NAF in diethyl ether; water
参考文献
SmithKline Beecham Corporation; Nycomed Austria GmbH
Patent: US6191146 B1, 2001 ;
反应条件
hydrogenchloride
1.) THF, r.t., 20 h; 2.) reflux, 1.5 h; Multistep reaction;
参考文献
Amemiya; Kojima; Okano; et al.
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 2 p. 873 - 875
反应条件
hydrogenchloride
1.) MeOH, THF, r.t., 38 h; 2.) reflux, 1.5 h; Multistep reaction;
参考文献
Amemiya; Kojima; Okano; et al.
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 2 p. 873 - 875
