1,3-二苄氧基-2-(氯甲氧基)丙烷合成路线 （共 8 条）
反应条件
ammonium sulfate; Hg(II) cyanide in ethanol; 1,1,1,3,3,3-hexamethyl-disilazane; benzene
参考文献
Ogilvie; Kelvin K.
Patent: US4508898 A1, 1985 ;
反应条件
hydrogenchloride in dichloromethane
T=0°C; 3 h;
参考文献
Singh, P. K.; Saluja, Sunita; Pratap, Ram; George, C. X.; Bhakuni, D. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 823 - 827
反应条件
paraformaldehyde in 1,2-dichloro-ethane
参考文献
Syntex (U.S.A.) Inc.
Patent: US4423050 A1, 1983 ;
Title/Abstract Full Text Show Details
Syntex (U.S.A.) Inc.
Patent: US4565868 A1, 1986 ;
Title/Abstract Full Text Show Details
Syntex Inc.
Patent: US5250535 A1, 1993 ;
Title/Abstract Full Text Show Details
Syntex (U.S.A.) Inc.
Patent: US4355032 A1, 1982 ;
反应条件
hydrogenchloride
T=0°C; 6 h;
参考文献
Ogilvie; Nguyen-Ba; Gillen; et al.
Canadian Journal of Chemistry, 1984 , vol. 62, # 2 p. 241 - 252
反应条件
1: dimethylformamide / Heating
2: HCl / CH2Cl2 / 0 °C
View Scheme
参考文献
Beauchamp, Lilia M.; Serling, Barbara L.; Kelsey, John E.; Biron, Karen K.; Collins, Peter; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 1 p. 144 - 149
反应条件
1: 1.) aq. NaOH / 2.) 16 h
2: HCl gas. / CH2Cl2 / 16 h / 0 °C
View Scheme
参考文献
Martin; Dvorak; Smee; Matthews; Verheyden
Journal of Medicinal Chemistry, 1983 , vol. 26, # 5 p. 759 - 761
反应条件
1: 24 percent / ammonia / methanol / Ambient temperature
2: HCl / 1,2-dichloro-ethane / 4 h / 0 °C
View Scheme
参考文献
Kovacs, Lajos; Herczegh, Pal; Batta, Gyula; Farkas, Istvan
Heterocycles, 1987 , vol. 26, # 4 p. 947 - 960
反应条件
ammonium sulfate; mercury(II) cyanide; 1,1,1,3,3,3-hexamethyl-disilazane
1.) 2 h, reflux; 2.) benzene, 3 h, reflux; Yield given. Multistep reaction;
参考文献
Ogilvie; Cheriyan; Radatus
Canadian Journal of Chemistry, 1982 , vol. 60, # 24 p. 3005 - 3010
