2-苄基-1H-吲哚-3-羧酸合成路线 （共 12 条）
反应条件
sodium hydroxide in ethanol
T=20°C; 3 h;
参考文献
Rekhter
Chemistry of Heterocyclic Compounds, 2005 , vol. 41, # 9 p. 1119 - 1120
反应条件
1: H2 / 10percent Pd-C / methanol
2: methanol / 25 °C
3: methanol; diethyl ether / 120 h / 25 °C
View Scheme
参考文献
Grigg, Ronald; Gunaratne, H. Q. Nimal
Journal of the Chemical Society, Chemical Communications, 1984 , # 10 p. 661 - 662
反应条件
1.1: NaH / dimethylformamide
1.2: 46 percent / dimethylformamide / 1 h / -15 - -10 °C
2.1: 87 percent / aq. NaOH / ethanol / 3 h / 20 °C
View Scheme
参考文献
Rekhter
Chemistry of Heterocyclic Compounds, 2005 , vol. 41, # 9 p. 1119 - 1120
反应条件
1.1: KI / dimethylformamide / 16 h / -10 °C
2.1: NaH / dimethylformamide
2.2: 46 percent / dimethylformamide / 1 h / -15 - -10 °C
3.1: 87 percent / aq. NaOH / ethanol / 3 h / 20 °C
View Scheme
参考文献
Rekhter
Chemistry of Heterocyclic Compounds, 2005 , vol. 41, # 9 p. 1119 - 1120
反应条件
1: dimethylformamide
2: 20percent aq. NaOH / 12 h / Heating
View Scheme
参考文献
Black, David St. C.; Wong, Laurence C. H.
Journal of the Chemical Society, Chemical Communications, 1980 , # 4 p. 200
反应条件
1: NaOH / methanol
2: dimethylformamide
3: 20percent aq. NaOH / 12 h / Heating
View Scheme
参考文献
Black, David St. C.; Wong, Laurence C. H.
Journal of the Chemical Society, Chemical Communications, 1980 , # 4 p. 200
参考文献
Ainley; Robinson
Journal of the Chemical Society, 1934 , p. 1508,1517
反应条件
1: methanol / 25 °C
2: methanol; diethyl ether / 120 h / 25 °C
View Scheme
参考文献
Grigg, Ronald; Gunaratne, H. Q. Nimal
Journal of the Chemical Society, Chemical Communications, 1984 , # 10 p. 661 - 662
反应条件
1: NaOH-solution; water; ethanol
2: aqueous NaOH
View Scheme
参考文献
Ainley; Robinson
Journal of the Chemical Society, 1934 , p. 1508,1517
反应条件
sodium hydroxide
12 h; Heating; Yield given. Yields of byproduct given;
参考文献
Black, David St. C.; Wong, Laurence C. H.
Journal of the Chemical Society, Chemical Communications, 1980 , # 4 p. 200
