4-氯-N-异丙基苯甲酰胺合成路线 （共 10 条）
反应条件
pyridine in tetrahydrofuran T=20°C; 0.75 h;
参考文献
Rahman, Obaidur; Kihlberg, Tor; Langstroem, Bengt
Journal of Organic Chemistry, 2003 , vol. 68, # 9 p. 3558 - 3562
反应条件
water; caesium carbonate in acetone T=0°C; 0.333333 h; Schlenk techniqueInert atmosphere;
参考文献
Xia, Zhonghua; Zhu, Qiang
Organic Letters, 2013 , vol. 15, # 16 p. 4110 - 4113
反应条件
chlorine in water; acetic acid T=70°C; 9 h;
参考文献
European Journal of Organic Chemistry, , # 8 p. 1689 - 1696
反应条件
1: hydrofluoroboric acid; sodium nitrite / water / 0.58 h / 0 °C 2: caesium carbonate; water / acetone / 0.33 h / 0 °C / |Schlenk technique; |Inert atmosphere View Scheme
参考文献
Organic Letters, , vol. 15, # 16 p. 4110 - 4113
反应条件
in tetrahydrofuran T=20°C; 2 h; Further byproducts given;
参考文献
Heteroatom Chemistry, , vol. 17, # 7 p. 676 - 684
反应条件
(i) (chlorination), (ii) /BRN= 605259/, benzene; Multistep reaction;
参考文献
Journal of medicinal chemistry, , vol. 11, # 5 p. 1023 - 1028
反应条件
in tetrahydrofuran 16 h;
参考文献
Heteroatom Chemistry, , vol. 19, # 3 p. 271 - 282
反应条件
in tetrahydrofuran 16 h; Further byproducts.;
参考文献
Heteroatom Chemistry, , vol. 19, # 3 p. 271 - 282
反应条件
1: Na2HPO4 / acetonitrile / 0 - 20 °C / 4-8 h 2: HCl / H2O / 4 h / Ambient temperature View Scheme
参考文献
Synthetic Communications, , vol. 27, # 5 p. 923 - 937
反应条件
1: Na2HPO4 / CH2Cl2 / 0 - 20 °C / 1-2 d 2: HCl / H2O / 96 h / Ambient temperature View Scheme
参考文献
Kiessling, Anthony J.; McClure, Cynthia K.
Synthetic Communications, 1997 , vol. 27, # 5 p. 923 - 937
