N,N-二乙基-4-甲氧基-苯甲酰胺合成路线 （共 48 条）
反应条件
1: diethylamine With ethylmagnesium bromide in tetrahydrofuran; diethyl ether
T=30°C; 1 h;
2: 2-methoxy 5-cyanobenzene With ethylmagnesium bromide in tetrahydrofuran; diethyl ether
T=30°C; 1 h;
3: With hydrogenchloride in tetrahydrofuran; diethyl ether; dichloromethane
T=22°C;
参考文献
Bhattacharya, Apurba; Plata, Robert Erik; Villarreal, Victor; Muramulla, Savitha; Wu, Jiejun
Tetrahedron Letters, 2006 , vol. 47, # 4 p. 505 - 506
反应条件
methyllithium in tetrahydrofuran; diethyl ether
T=-65°C; 0.0166667 h;
参考文献
Patterson, John W.
Journal of Organic Chemistry, 1995 , vol. 60, # 14 p. 4542 - 4548
反应条件
NiCl2((PPh3)P)2 in tetrahydrofuran
T=20°C; 2 h;
参考文献
Lemoucheux; Rouden; Lasne
Tetrahedron Letters, 2000 , vol. 41, # 51 p. 9997 - 10001
反应条件
tris-(dibenzylideneacetone)dipalladium(0); di-tert-butyl(2′,4′,6′-triisopropylbiphenyl-2-yl)phosphine in N,N-dimethyl-formamide
T=100°C; Inert atmosphere;
参考文献
Tolnai, Gergely L.; Petho, Balint; Krall, Peter; Novaka, Zoltan
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 1 p. 125 - 129
反应条件
1: ethyl tribromoacetate; triphenylphosphine / CH2Cl2 / 3 h / 20 °C
2: Et3N / CH2Cl2 / 1 h / 20 °C
View Scheme
参考文献
Kang, Dong Ho; Joo, Tae Young; Lee, Eun Hwa; Chaysripongkul, Skaydaw; Chavasiri, Warinthorn; Jang, Doo Ok
Tetrahedron Letters, 2006 , vol. 47, # 32 p. 5693 - 5696
反应条件
dipotassium peroxodisulfate; palladium diacetate in water; dimethyl sulfoxide; acetonitrile
T=20°C;
参考文献
Li, Mingzong; Wang, Cong; Fang, Ping; Ge, Haibo
Chemical Communications, 2011 , vol. 47, # 23 p. 6587 - 6589
参考文献
Couturier
Annales de Chimie (Cachan, France), 1938 , vol. <11> 10, p. 559,597
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; oxygen in dimethyl sulfoxide
4 h;
参考文献
Yuste, Francisco; Origel, Alfredo E.; Brena, Leonardo J.
Synthesis, 1983 , # 2 p. 109 - 110
反应条件
PdCl2(PMePh2)2 in neat (no solvent)
T=100°C; P=10 Torr; 24 h; Product distributionMechanism;
参考文献
Ozawa, Fumiyuki; Soyama, Hidehiko; Yanagihara, Hisayoshi; Aoyama, Issei; Takino, Hiroaki; et al.
Journal of the American Chemical Society, 1985 , vol. 107, # 11 p. 3235 - 3245
反应条件
PdCl2(PMePh2)2 in neat (no solvent)
T=80°C; P=50 Torr; 1.5 h; Product distributionMechanism;
参考文献
Ozawa, Fumiyuki; Soyama, Hidehiko; Yanagihara, Hisayoshi; Aoyama, Issei; Takino, Hiroaki; et al.
Journal of the American Chemical Society, 1985 , vol. 107, # 11 p. 3235 - 3245
