(4-溴苯基)(哌啶-4-基)甲酮合成路线 （共 3 条）
反应条件
in methanol T=20°C; 2 h;
参考文献
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH; NACRO, Kassoum; DURAISWAMY, Athisayamani, Jeyaraj; CHENNAMANENI, Lohitha, Rao
Patent: WO2013/147711 A1, 2013 ;
Location in patent: Page/Page column 231 ;
反应条件
potassium carbonate in methanol; water
T=20°C; 18 h;
参考文献
Burnett, Duane A.; Wu, Wen-Lian; Sasikumar, Thavalakulamgara K.; Greenlee, William J.; Caplen, Mary Ann; Guo, Tao; Hunter, Rachael Catherine
Patent: US2005/54628 A1, 2005 ;
Location in patent: Page/Page column 23-24; 10 ;
US 20050054628 A1
反应条件
hydrogenchloride; water
RefluxInert atmosphere;
参考文献
Tu, Zhude; Efange, Simon M. N.; Xu, Jinbin; Li, Shihong; Jones, Lynne A.; Parsons, Stanley M.; Mach, Robert H.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 5 p. 1358 - 1369
