3-氨基-n-[2-(4-吗啉)乙基]苯甲酰胺合成路线 （共 3 条）
反应条件
5 palladium on charcoal; hydrogen in methanol
T=20°C; P=760.051 Torr; Inert atmosphere;
参考文献
Naik, Ravi; Won, Misun; Kim, Bo-Kyung; Xia, Yan; Choi, Hyun Kyung; Jin, Guanghai; Jung, Youngjin; Kim, Hwan Mook; Lee, Kyeong
Journal of Medicinal Chemistry, 2012 , vol. 55, # 23 p. 10564 - 10571
反应条件
1: benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 20 °C / |Inert atmosphere
2: 5 palladium on charcoal; hydrogen / methanol / 20 °C / 760.05 Torr / |Inert atmosphere
View Scheme
参考文献
Naik, Ravi; Won, Misun; Kim, Bo-Kyung; Xia, Yan; Choi, Hyun Kyung; Jin, Guanghai; Jung, Youngjin; Kim, Hwan Mook; Lee, Kyeong
Journal of Medicinal Chemistry, 2012 , vol. 55, # 23 p. 10564 - 10571
反应条件
1: benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 20 °C / |Inert atmosphere
2: 5 palladium on charcoal; hydrogen / methanol / 20 °C / 760.05 Torr / |Inert atmosphere
View Scheme
参考文献
Naik, Ravi; Won, Misun; Kim, Bo-Kyung; Xia, Yan; Choi, Hyun Kyung; Jin, Guanghai; Jung, Youngjin; Kim, Hwan Mook; Lee, Kyeong
Journal of Medicinal Chemistry, 2012 , vol. 55, # 23 p. 10564 - 10571
