3-氨基-3-环丁基甲基-2-羟基丙酰胺合成路线 （共 1 条）
反应条件
1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide; dichloromethane / 0 - 30 °C 2: hydrogenchloride / isopropyl alcohol / 6 h / 60 - 65 °C 3: N-ethyl-N,N-diisopropylamine; HATU / acetonitrile / 5 h / 25 - 30 °C 4: Dess-Martin periodane / dichloromethane / 0 - 30 °C View Scheme
参考文献
MSN LABORATORIES LIMITED; THIRUMALAI RAJAN, Srinivasan; ESWARAIAH, Sajja; VENKAT REDDY, Ghojala; SAHADEVA REDDY, Maramreddy
Patent: WO2014/61034 A1, 2014 ;
