1,5-二(4-氰基苯氧基)戊烷合成路线 （共 8 条）
反应条件
ammonia methyl alcohol; nickel T=110°C; P=66195.7 Torr; Hydrogenation;
参考文献
Kramp, Kari L.; DeWitt, Kristin; Flora, Jason W.; Muddiman, David C.; Slunt, Kelli M.; Houston, Todd A.
Tetrahedron Letters, 2005 , vol. 46, # 4 p. 695 - 698
反应条件
1: HCl (gas) / benzene / 72 h / Ambient temperature 2: ethanol. NH3 / 6 h / 50 °C View Scheme
参考文献
Tidwell; Jones; Geratz; Ohemeng; Cory; Hall
Journal of Medicinal Chemistry, 1990 , vol. 33, # 4 p. 1252 - 1257
反应条件
hydrogenchloride; nitrobenzene
参考文献
Reynaud,P. et al.
Bulletin de la Societe Chimique de France, 1964 , p. 3155 - 3158
反应条件
sodium hydride in N,N-dimethyl-formamide
T=80°C; 1 h;
参考文献
Gromyko; Popov; Mosoleva; Streltsov; Grokhovsky; Oleinikov; Zhuze
Russian Journal of Bioorganic Chemistry, 2005 , vol. 31, # 4 p. 344 - 351
反应条件
1: 88 percent / 4percent KOH / ethanol / 0.33 h / Heating
2: 1.) aq. NaOH / 1.) C2H5OH, reflux, 1 h, 2.) C2H5OH, reflux, 3 h
View Scheme
参考文献
Nandi, Gopa; Mukherjee, S.; Basu, M. K.; Mahato, Shashi B.
Journal of the Indian Chemical Society, 1993 , vol. 70, # 6 p. 527 - 532
反应条件
1: 82 percent / 1 h / Heating
2: 88 percent / 4percent KOH / ethanol / 0.33 h / Heating
3: 1.) aq. NaOH / 1.) C2H5OH, reflux, 1 h, 2.) C2H5OH, reflux, 3 h
View Scheme
参考文献
Nandi, Gopa; Mukherjee, S.; Basu, M. K.; Mahato, Shashi B.
Journal of the Indian Chemical Society, 1993 , vol. 70, # 6 p. 527 - 532
参考文献
Ashley et al.
Journal of the Chemical Society, 1942 , p. 103,107
反应条件
1: HCl (gas) / benzene / 72 h / Ambient temperature
2: methanol / 3 h / Heating
View Scheme
参考文献
Tidwell; Jones; Geratz; Ohemeng; Cory; Hall
Journal of Medicinal Chemistry, 1990 , vol. 33, # 4 p. 1252 - 1257
