4,5,7-三甲氧基-2-萘羧酸甲酯合成路线 （共 18 条）
参考文献
Aventis Pharma S.A.
Patent: EP1300403 A1, 2003 ;
反应条件
lithium aluminium tetrahydride in diethyl ether 3 h;
参考文献
Green, Ivan R.; Giles, Robin G.F.; Gruchlik, Yolanta
South African Journal of Chemistry, 1997 , vol. 50, # 2 p. 75 - 81
反应条件
potassium carbonate in acetone
12 h; Heating;
参考文献
Cameron, Donald W.; Feutrill, Geoffrey I.; Pannan, Linda J. H.
Australian Journal of Chemistry, 1980 , vol. 33, # 11 p. 2531 - 2541
反应条件
1: 82 percent / benzene / 288 h / 20 °C
2: 63 percent / potassium acetate / 0.25 h / Heating
3: 93 percent / potassium carbonate; methanol / acetone / 3 h / 35 °C
4: potassium carbonate / acetone / 16 h / Heating
View Scheme
参考文献
Piettre, Arnaud; Chevenier, Emmanuel; Massardier, Christine; Gimbert, Yves; Greene, Andrew E.
Organic Letters, 2002 , vol. 4, # 18 p. 3139 - 3142
反应条件
1: 93 percent / potassium carbonate; methanol / acetone / 3 h / 35 °C
2: potassium carbonate / acetone / 16 h / Heating
View Scheme
参考文献
Piettre, Arnaud; Chevenier, Emmanuel; Massardier, Christine; Gimbert, Yves; Greene, Andrew E.
Organic Letters, 2002 , vol. 4, # 18 p. 3139 - 3142
反应条件
1: 63 percent / potassium acetate / 0.25 h / Heating
2: 93 percent / potassium carbonate; methanol / acetone / 3 h / 35 °C
3: potassium carbonate / acetone / 16 h / Heating
View Scheme
参考文献
Piettre, Arnaud; Chevenier, Emmanuel; Massardier, Christine; Gimbert, Yves; Greene, Andrew E.
Organic Letters, 2002 , vol. 4, # 18 p. 3139 - 3142
反应条件
potassium carbonate in acetone
16 h; Heating;
参考文献
Piettre, Arnaud; Chevenier, Emmanuel; Massardier, Christine; Gimbert, Yves; Greene, Andrew E.
Organic Letters, 2002 , vol. 4, # 18 p. 3139 - 3142
反应条件
in trifluoroacetic acid
Ambient temperature;
参考文献
Cameron, Donald W.; Feutrill, Geoffrey I.; Pannan, Linda J. H.; Raston, Colin L.; Skelton, Brian W.; White, Allan H.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1981 , p. 610 - 627
参考文献
Cameron, Donald W.; Feutrill, Geoffrey I.; Pannan, Linda J. H.
Australian Journal of Chemistry, 1980 , vol. 33, # 11 p. 2531 - 2541
反应条件
1: 44 percent / 230 °C
2: 1.) 48percent aq. HBr, 2.) dimethyl sulfate, K2CO3 / 1.) reflux, 3 h, 2.) acetone, reflux, 18 h
View Scheme
参考文献
Cameron, Donald W.; Feutrill, Geoffrey I.; Pannan, Linda J. H.
Australian Journal of Chemistry, 1980 , vol. 33, # 11 p. 2531 - 2541
