7-氯-5-甲氧基-噻吩并[3,2-b]吡啶合成路线 （共 7 条）
反应条件
in methanol
2 h; Heating;
参考文献
Barker, John M.; Huddleston, Patrick R.; Chadwick, Nigel; Keenan, Guy J.
Journal of Chemical Research, Miniprint, 1980 , # 1 p. 113 - 126
参考文献
Jarvest, Richard L.; Armstrong, Sula A.; Berge, John M.; Brown, Pamela; Elder, John S.; Brown, Murray J.; Copley, Royston C.B.; Forrest, Andrew K.; Hamprecht, Dieter W.; O'Hanlon, Peter J.; Mitchell, Darren J.; Rittenhouse, Stephen; Witty, David R.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 15 p. 3937 - 3941
反应条件
1: 88 percent / 1.5 h / Heating
2: 73 percent / NaOEt / ethanol / 8 h / Heating
3: 1) 20percent aq. NaOH, 2) conc. HCl / 1) heating, 2 h, 2) heating
4: 9 percent / POCl3 / 3 h / Heating
5: diethyl ether
View Scheme
参考文献
Barker, John M.; Huddleston, Patrick R.; Chadwick, Nigel; Keenan, Guy J.
Journal of Chemical Research, Miniprint, 1980 , # 1 p. 113 - 126
反应条件
1: 9 percent / POCl3 / 3 h / Heating
2: diethyl ether
View Scheme
参考文献
Barker, John M.; Huddleston, Patrick R.; Chadwick, Nigel; Keenan, Guy J.
Journal of Chemical Research, Miniprint, 1980 , # 1 p. 113 - 126
反应条件
1: 1) 20percent aq. NaOH, 2) conc. HCl / 1) heating, 2 h, 2) heating
2: 9 percent / POCl3 / 3 h / Heating
3: diethyl ether
View Scheme
参考文献
Barker, John M.; Huddleston, Patrick R.; Chadwick, Nigel; Keenan, Guy J.
Journal of Chemical Research, Miniprint, 1980 , # 1 p. 113 - 126
反应条件
1: 73 percent / NaOEt / ethanol / 8 h / Heating
2: 1) 20percent aq. NaOH, 2) conc. HCl / 1) heating, 2 h, 2) heating
3: 9 percent / POCl3 / 3 h / Heating
4: diethyl ether
View Scheme
参考文献
Barker, John M.; Huddleston, Patrick R.; Chadwick, Nigel; Keenan, Guy J.
Journal of Chemical Research, Miniprint, 1980 , # 1 p. 113 - 126
参考文献
Barker, John M.; Huddleston, Patrick R.; Chadwick, Nigel; Keenan, Guy J.
Journal of Chemical Research, Miniprint, 1980 , # 1 p. 113 - 126
