3-乙酰基-7-二乙基氨基-2H-色烯-2-酮合成路线 （共 14 条）
反应条件
amino acid fuctionalized Fe3O4 nanoparticles(Fe3O4-DA-Phe) in neat (no solvent)
T=130°C; Knoevenagel Condensation; 0.0833333 h; Microwave irradiationGreen chemistry;
参考文献
Girija; Naik, H.S. Bhojya; Kumar, B. Vinay; Sudhamani; Harish
Letters in Organic Chemistry, 2013 , vol. 10, # 7 p. 468 - 477
反应条件
piperidine in ethanol
Knoevenagel cyclization;
参考文献
Secci, Daniela; Carradori, Simone; Bolasco, Adriana; Chimenti, Paola; Yanez, Matilde; Ortuso, Francesco; Alcaro, Stefano
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 10 p. 4846 - 4852
反应条件
piperidine in ethanol
0.5 h; Heating;
参考文献
Czerney, P.; Hartmann, H.
Journal fuer Praktische Chemie (Leipzig), 1982 , vol. 324, # 1 p. 21 - 28
反应条件
morpholine in ethanol
2 h; Reflux;
参考文献
Chen, Jianhong; Liu, Weimin; Ma, Jingjin; Xu, Haitao; Wu, Jiasheng; Tang, Xianglin; Fan, Zhiyuan; Wang, Pengfei
Journal of Organic Chemistry, 2012 , vol. 77, # 7 p. 3475 - 3482
反应条件
piperidine in ethanol
0.5 h; Heating;
参考文献
Czerney, P.; Hartmann, H.
Journal fuer Praktische Chemie (Leipzig), 1982 , vol. 324, # 1 p. 21 - 28
反应条件
mercury(II) diacetate; water in dimethyl sulfoxide
T=25°C; Kucherov reaction; pH=7.4; 1 h; aq. buffer;
参考文献
Lee, Dong-Nam; Kim, Gun-Joong; Kim, Hae-Jo
Tetrahedron Letters, 2009 , vol. 50, # 33 p. 4766 - 4768
反应条件
1: bromine; acetic acid / 20 °C
2: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / N,N-dimethyl-formamide / 5 h / 60 °C / Inert atmosphere
3: methanol; tetrabutyl ammonium fluoride / tetrahydrofuran / 8 h / 20 °C
4: mercury(II) diacetate; water / dimethyl sulfoxide / 1 h / 25 °C / pH 7.4 / aq. buffer
View Scheme
参考文献
Lee, Dong-Nam; Kim, Gun-Joong; Kim, Hae-Jo
Tetrahedron Letters, 2009 , vol. 50, # 33 p. 4766 - 4768
反应条件
1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / N,N-dimethyl-formamide / 5 h / 60 °C / Inert atmosphere
2: methanol; tetrabutyl ammonium fluoride / tetrahydrofuran / 8 h / 20 °C
3: mercury(II) diacetate; water / dimethyl sulfoxide / 1 h / 25 °C / pH 7.4 / aq. buffer
View Scheme
参考文献
Lee, Dong-Nam; Kim, Gun-Joong; Kim, Hae-Jo
Tetrahedron Letters, 2009 , vol. 50, # 33 p. 4766 - 4768
反应条件
1: piperidine / ethanol / |Reflux
2: hydrogenchloride / water / 100 °C
3: trichlorophosphate / 60 °C
View Scheme
参考文献
Sanap, Kailas K.; Samant, Shriniwas D.
Synlett, 2012 , vol. 23, # 15 p. 2189 - 2194
反应条件
1: hydrogenchloride / water / 100 °C
2: trichlorophosphate / 60 °C
View Scheme
参考文献
Sanap, Kailas K.; Samant, Shriniwas D.
Synlett, 2012 , vol. 23, # 15 p. 2189 - 2194
