1-(3-溴苯基)-1-甲基乙胺合成路线 (共 3 条)
反应条件
1: methyllithium With cerium(III) chloride in tetrahydrofuran; diethyl ether 0.5 h; Cooling with acetone-dry ice; 2: meta-bromobenzonitrile in tetrahydrofuran; diethyl ether
参考文献
EP2119703 A1, ;
Page/Page column 36-37 ;
反应条件
1: With acetic acid; thiourea in ethanol 10 h; Heating / reflux; 2: With sodium hydroxide in water pH=7 - 8;
参考文献
WO2005/70932 A2, ;
Page/Page column 51-52 ;
WO 2005/070932 A2
反应条件
hydrogenchloride in diethyl ether
参考文献
ELAN PHARMACEUTICALS, INC.; PHARMACIA and UP JOHN COMPANY
Patent: WO2005/95326 A2, 2005 ;
Location in patent: Page/Page column 190 ;
WO 2005/095326 A2