4-溴甲基-2-甲基苯甲酸甲酯合成路线 （共 15 条）
反应条件
bromine in tetrachloromethane 1.75 h; Heating / refluxIrradiation;
参考文献
ELI LILLY AND COMPANY
Patent: WO2004/108677 A1, 2004 ;
Location in patent: Page 199 ;
WO 2004/108677 A1
反应条件
N-bromosuccinmide; CH3I; potassium carbonate; azobisisobutyronitrile in tetrachloromethane; diethyl ether; acetone
参考文献
US6265416 B1, ;
US 6265416 B1
反应条件
N-bromosuccinmide in tetrachloromethane; ethyl acetate
参考文献
US5302601 A1, ;
US 5302601 A
反应条件
1: With potassium carbonate in acetone 96 h; Heating / reflux; 2: With N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in tetrachloromethane 4 h; Heating / reflux;
参考文献
Eli Lilly and Company
Patent: US6359136 B1, 2002 ;
Location in patent: Example 1C ;
反应条件
in tetrachloromethane
反应条件
1: aq. NaOH 2: aq. NaOCl 3: Br2, AlCl3 / CCl4 / Irradiation 4: HCl View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 2255 - 2261
反应条件
1: AlCl3 / 165 °C 2: aq. NaOH 3: aq. NaOCl 4: Br2, AlCl3 / CCl4 / Irradiation 5: HCl View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 2255 - 2261
反应条件
1: aq. NaOCl 2: Br2, AlCl3 / CCl4 / Irradiation 3: HCl View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 2255 - 2261
反应条件
1: Br2, AlCl3 / CCl4 / Irradiation 2: HCl View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 2255 - 2261
反应条件
N-bromosuccinmide in tetrachloromethane 4 h; Irradiation;
参考文献
Bioorganic and medicinal chemistry, , vol. 10, # 9 p. 3013 - 3021
