5-硝基-6-氯烟酸合成路线

MERCK SHARP andamp; DOHME CORP.; CHU, Lin; OGAWA, Anthony; OK, Hyun, O.; UJJAINWALLA, Feroze
Patent: WO2010/51245 A1, 2010 ;
Location in patent: Page/Page column 34 ;
WO 2010/051245 A1

67-56-1甲醇+

7477-10-35-硝基-6-氯烟酸

59237-53-56-氯-5-硝基烟酸甲酯

参考文献

Brooks, Gerald; Dabbs, Steven; Davies, David T.; Hennessy, Alan J.; Jones, Graham E.; Markwell, Roger E.; Miles, Timothy J.; Owston, Nathan A.; Pearson, Neil D.; Peng, Tony W.
Tetrahedron Letters, 2010 , vol. 51, # 38 p. 5035 - 5037

7477-10-35-硝基-6-氯烟酸

321845-13-0(5-氨基-6-氯吡啶-3-基)甲醇

参考文献

Kagabu; Maienfisch; Zhang; Granda-Minones; Haettenschwiler; Kayser; Maetzke; Casida
Journal of Medicinal Chemistry, 2000 , vol. 43, # 26 p. 5003 - 5009

64-17-5乙醇+

7477-10-35-硝基-6-氯烟酸

171876-22-56-氯-5-硝基吡啶-3-甲酸乙酯

参考文献

Skouta, Rachid; Dixon, Scott J.; Wang, Jianlin; Dunn, Denise E.; Orman, Marina; Shimada, Kenichi; Rosenberg, Paul A.; Lo, Donald C.; Weinberg, Joel M.; Linkermann, Andreas; Stockwell, Brent R.
Journal of the American Chemical Society, 2014 , vol. 136, # 12 p. 4551 - 4556

7477-10-35-硝基-6-氯烟酸

7477-11-48-硝基-四唑并[1,5-a]吡啶-6-羧酸

参考文献

Boyer; Schoen
Journal of the American Chemical Society, 1956 , vol. 78, p. 423

7647-01-0盐酸+

67-56-1甲醇+

7477-10-35-硝基-6-氯烟酸

7477-11-48-硝基-四唑并[1,5-a]吡啶-6-羧酸

参考文献

Boyer; Schoen
Journal of the American Chemical Society, 1956 , vol. 78, p. 423