3-(1-吡咯)噻吩-2羧酸甲酯合成路线 （共 6 条）
反应条件
in acetic acid 1) 80 deg C, 30 min, 2) reflux, 1 h;
参考文献
Rault, Sylvain; Effi, Yamien; Sevricourt, Michel Cugnon de; Lancelot, Jean-Charles; Robba, Max
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 17 - 21
反应条件
acetic acid 2 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 39, # 10 p. 2068 - 2080
反应条件
aluminium trichloride in carbon disulfide 2 h; Heating;
参考文献
Effi; Lancelot; Rault; Robba
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 1 p. 17 - 23
反应条件
sodium hydroxide 2.5 h; Heating;
参考文献
Adir et Compagnie
Patent: US5627203 A1, 1997 ;
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
参考文献
Rault, Sylvain; Effi, Yamien; Lancelot, Jean-Charles; Robba, Max
Heterocycles, 1986 , vol. 24, # 3 p. 575 - 578
反应条件
1: NaOH / H2O; methanol / 3 h / Heating
2: NaN3, TEA, ClCO2Et / acetone; acetonitrile / 0 °C
View Scheme
参考文献
Rault, Sylvain; Effi, Yamien; Sevricourt, Michel Cugnon de; Lancelot, Jean-Charles; Robba, Max
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 17 - 21
