(1R,2S)-1-氨基-2-茚满醇合成路线 (共 78 条)
反应条件
sulfuric acid in water; acetonitrile
反应条件
sodium hydroxide; sulfuric acid in dichloromethane; acetonitrile
反应条件
potassium hydroxide in ethanol 16 h; Heating;
参考文献
Ghosh, Arun K.; Kincaid, John F.; Haske, Michael G.
Synthesis, 1997 , # 5 p. 541 - 544
反应条件
triphenylphosphine in tetrahydrofuran; ethyl acetate
反应条件
sulfuric acid in sodium hydroxide; dichloromethane; water; acetonitrile
反应条件
sulfuric acid in water; acetonitrile
反应条件
sulfuric acid in water; acetonitrile
参考文献
DSM N.V.
Patent: US6235927 B1, 2001 ;
反应条件
1: With (S)-(+)-2-phenylpropionic acid in ethanol 2: in water pH=12.5;
参考文献
Sakurai, Rumiko; Sakai, Kenichi
Tetrahedron Asymmetry, 2003 , vol. 14, # 4 p. 411 - 413
反应条件
1: 55 percent / MCPBA, NaHCO3 / CH2Cl2; H2O / 12 h / 23 °C 2: 78 percent / NaN3, NH4Cl / aq. ethanol / 10 h / Heating 4: 68 percent / H2 / 10percent Pd/C / ethyl acetate / 12 h / 23 °C 5: 86 percent / SOCl2 / 12 h / 23 °C 6: 87 percent / aq. KOH / ethanol / 16 h / Heating View Scheme
参考文献
Synthesis, , # 5 p. 541 - 544