(1R,2S)-1-氨基-2-茚满醇合成路线 (共 78 条)
反应条件
sodium hydroxide in isopropyl alcohol
参考文献
Brands, Karel M. Jos; Payack, Joseph F.; Pye, Philip J.
Patent: US2002/52493 A1, 2002 ;
反应条件
sodium carbonate in tetrahydrofuran; water T=0 - 20°C; 3 h; Inert atmosphere;
参考文献
Gao, Yaojun; Ren, Qiao; Wu, Hao; Li, Maoguo; Wang, Jian
Chemical Communications, 2010 , vol. 46, # 48 p. 9232 - 9234
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Ren, Qiao; Gao, Yaojun; Wang, Jian
Chemistry - A European Journal, 2010 , vol. 16, # 46 p. 13594 - 13598
反应条件
in dichloromethane T=20°C; 0.0833333 h;
参考文献
Shimizu, Mamoru; Sodeoka, Mikiko
Heterocycles, 2008 , vol. 76, # 2 p. 1301 - 1312
反应条件
1: With (S)-(+)-2-phenylpropionic acid in ethanol 2: in water pH=12.5;
参考文献
Sakurai, Rumiko; Sakai, Kenichi
Tetrahedron Asymmetry, 2003 , vol. 14, # 4 p. 411 - 413
参考文献
Thompson; Fitzgerald; Holloway; Emini; Darke; McKeever; Schleif; Quintero; Zugay; Tucker; Schwering; Homnick; Nunberg; Springer; Huff
Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1685 - 1701
反应条件
1: EDC, HOBT, TEA / dimethylformamide 2: tetrabutylammonium fluoride / tetrahydrofuran View Scheme
参考文献
Lyle, Terry A.; Wiscount, Catherine M.; Guare, James P.; Thompson, Wayne J.; Anderson, Paul S.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 3 p. 1228 - 1230
反应条件
1: With (S)-(+)-2-phenylpropionic acid in ethanol 2: in water pH=12.5;
参考文献
Sakurai, Rumiko; Sakai, Kenichi
Tetrahedron Asymmetry, 2003 , vol. 14, # 4 p. 411 - 413
参考文献
Thompson; Fitzgerald; Holloway; Emini; Darke; McKeever; Schleif; Quintero; Zugay; Tucker; Schwering; Homnick; Nunberg; Springer; Huff
Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1685 - 1701
反应条件
1: With (S)-(+)-2-phenylpropionic acid in ethanol 2: in water pH=12.5;
参考文献
Sakurai, Rumiko; Sakai, Kenichi
Tetrahedron Asymmetry, 2003 , vol. 14, # 4 p. 411 - 413
参考文献
Thompson; Fitzgerald; Holloway; Emini; Darke; McKeever; Schleif; Quintero; Zugay; Tucker; Schwering; Homnick; Nunberg; Springer; Huff
Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1685 - 1701